Program in Physical and Chemical Biology

PCBio Mentors and their Research Interests

(listed alphabetically)

Erin Adams Ph.D., Biochemistry and Molecular Biology
           Structure-function analysis of the immune system

Douglas Bishop Ph.D., Dept. Molecular Genetics and Cell Biology
           Molecular biology and genetic analysis of DNA recombination
           Peptide antagonists of DNA repair

Sean Crosson Ph.D., Dept. Biochemistry & Molecular Biology
           Signal detection and transduction in bacteria

Aaron Dinner Ph.D, Dept. Chemistry
           Signaling in the immune system

Margaret Gardel Ph.D., Dept. Physics
           Biophysical behaviors of the cellular cytoskeleton

Karl Freed Ph.D, Dept. Chemistry
           Protein dynamics, aggregation and folding

Benjamin Glick Ph.D., Dept. Molecular Genetics and Cell Biology
           Cell biology and genetics of Golgi biogenesis
           Novel methods for time-lapse fluorescence microscopy

Michael Glotzer Ph.D, Dept. Molecular Genetics and Cell Biology
           Molecular control of cytokinesis

Steve A.N. Goldstein M.D.-Ph.D., Dept. Pediatrics
           Ion channel structure and function

Jean Greenberg Ph.D., Dept. Molecular Genetics and Cell Biology
           Genetic regulation of plant responses to bacterial pathogens
           Proteomic analysis by mass spectrometry

Geoffrey Greene Ph.D., Ben May Cancer Research Institute and Dept. Biochemistry & Mol. Biol.
           Molecular biology of estrogen regulated gene expression
           Discovery of new chemical modulators of estrogen receptor

Robert Haselkorn Ph.D., Depts. Chemistry, Biochemistry & Mol. Biol. and Mol. Gen. and Cell Biol.
            Nitrogen fixing bacteria, genomics and molecular biology
           Genome scale analysis of bacteria

Chuan He Ph.D, Dept. Chemistry
            DNA repair
           Metal ion biosensors

Rustem Ismagilov, Ph.D, Dept. Chemistry
            Microfluidic approaches to the study of complex systems

Richard B. Jones Ph.D., Ben May Department for Cancer Research
           Growth factor signaling in human cells
           Systems-level approaches: protein microarrays and mass spectrometry

Robert Josephs Ph.D., Dept. Molecular Genetics and Cell Biology
           Advanced electron microscopies and structural analysis
           New methods for electron crystallography

Bob Keenan Ph.D., Dept. Biochemistry & Molecular Biology
           Structural biology and directed evolution
           Fluorescent Proteins

Stephen Kent Ph.D., Depts. Chemistry and Biochemistry & Molecular Biology
           Protein design by native chemical ligation

Shohei Koide Ph.D., Dept. Biochemistry & Molecular Biology
           Structural biology and protein engineering
           Protein-based nanomaterials

David Kovar Ph.D., Molecular Genetics and Cell Biology
           Cellular coordination of actin filament assembly
           Real time single actin filament imaging

Sergey Kozmin Ph.D, Dept. Chemistry
           Chemical biology of natural products
           Small molecule libraries to probe signaling pathways

Stephen Kron M.D.-Ph.D., Dept. Molecular Genetics and Cell Biology
           Cell cycle, checkpoint and signaling pathways in yeast
           Novel methods for functional biochips

Ka Yee Lee Ph.D, Dept. Chemistry
           Biophysical Chemistry
           Lipid-Protein Interactions
           Membranes Biophysics

Manyuan Long Ph.D., Dept. Ecology and Evolution
           Genome scale analysis of gene evolution and function

Marvin Makinen M.D.-Ph.D., Dept. Biochemistry & Molecular Biology
           Structural biology/structural basis of enzyme function/enzyme
           Kinetics/metalions in biology/electron magnetic resonance

Elizabeth McNally M.D.-Ph.D., Depts. Medicine and Human Genetics
           Roles of dystrophin associated glycoproteins in muscular dystrophies

Stephen Meredith M.D.-Ph.D., Dept. Biochemistry & Molecular Biology
           Proteinaggregation in disease

Dominique Missiakas Ph.D.,Dept. Microbiology
           Stress signaling in bacteria

Keith Moffat Ph.D, Dept. Biochemistry & Molecular Biology
           Molecular mechanisms of light-dependent signal transduction
           Time-resolved X-ray crystallography

Milan Mrksich Ph.D, Dept. Chemistry
           Surface Chemistries to study Cell Adhesion and Migration
           Drug discovery

Piers Nash Ph.D., Ben May Department for Cancer Research
            Protein-protein recognition via domain interactions
           Proteomic methods for analyzing complexes

Marcelo Nobrega MD, PhD., Department of Human Genetics
            Gene regulation and regulatory mutations in human diseases

James Norris Ph.D, Dept. Chemistry
           Probing reactive oxygen species in human and animal cells
           Using light to label molecules involved in cell biochemistry

Tao Pan Ph.D., Dept. Biochemistry & Molecular Biology
           Functional genomics of tRNA; RNA folding

Joseph Piccirilli Ph.D., Depts. Chemistry and Biochemistry & Molecular Biology
           Chemistry of RNA splicing and catalysis

Daphne Preuss, Ph.D., Dept. Molecular Genetics and Cell Biology
           Plant fertilization and development
           High throughput genomic and genetic methods

Viresh Rawal Ph.D, Dept. Chemistry
           Chemical synthesis and study of bioactive natural products

Ilaria Rebay Ph.D., Ben May Department for Cancer Research
           Signaling networks in animal development

Phoebe Rice Ph.D., Dept. Biochemistry & Molecular Biology
           Structural biology and molecular mechanisms of mobile DNA

Ronald Rock Ph.D, Dept. Biochemistry and Molecular Biology
           Single-molecule studies of myosin

Bernard Roizman Ph.D., Dept. Molecular Genetics and Cell Biology
           Herpes virus virulence
           Gene expression array technology

Marsha Rosner Ph.D., Ben May Department for Cancer Research
           MAPK signaling in cell differentiation
           Novel chemical probes of cell signaling

Norbert Scherer Ph.D., Dept. Chemistry
           Novel spectroscopies and single molecule approaches

Olaf Schneewind M.D.-Ph.D., Dept. Microbiology
           Bacterial virulence by Type III pilli
           Proteomic analysis of virulence factors

Nancy Schwartz Ph.D., Dept. Biochemistry & Molecular Biology
           Extracellular matrix function and development

Ridgway Scott Ph.D., Depts. of Computer Science and of Mathematics
           protein-ligand interaction and solvation
           Distributed computing, bioinformatics

Harinder Singh Ph.D., Dept. Molecular Genetics and Cell Biology
           Early hematopoietic development
           Discovering regulatory motifs by computational approaches

Tobin Sosnick Ph.D., Dept. Biochemistry & Molecular Biology
           Peptide and RNA models for folding

Ursula Storb M.D., Dept. Molecular Genetics and Cell Biology
           Somatic hypermutation and DNA repair

Wei-Jen Tang Ph.D., Ben May Department for Cancer Research
           Structural biology of bacterial toxins and amyloid-beta degrading proteases
           Drug discovery

Jun Yin Ph.D., Dept. Chemistry
           Enzyme evolution and natural product biosynthesis