Burroughs Wellcome Fund Interfaces in Science
Cross-Disciplinary Program in Biophysical Dynamics and Biocomplexity

BWF Homepage Note To Faculty Visiting Scholars
Requirements & Resources Fellows and Mentors Biophysical Discussions
Guidelines for Application Administration Other Courses
Further Description Presentations by Fellows  

This course is sponsored jointly by the Burroughs Wellcome Interfaces program and Committee on Cell Physiology; credit is granted for qualified students meeting the requirements of the course directors.


Spring Quarter 2006 Cell Physiology 350 Biophysical Discussions: Systems Biology, Self-Assembly and Complexity
Course Director: Piers Nash

  • April 3: Reductionist approaches to systems and self assembly: Simple experiments to probe complexity
    Norbert Scherer (Chemistry)
    Steve Kron (Molecular Genetics and Cell Biology)
  • April 10: Molecular assembly to mechanical support: Probing the actin cytoskeleton
    Sergey Kozmin (Chemistry)
    David Kovar (Molecular Genetics and Cell Biology)
  • April 17: Complex materials and complex networks
    Thomas Witten (Physics)
    Thuong Van Ha (Radiology)
  • April 24: DNA-protein interactions: Transcriptional activation and recombination
    Chuan He (Chemistry)
    Phoebe Rice (Biochemistry and Molecular Biology)
  • May 1: Self-organization of biological and physical nanostructures
    Heinrich Jaeger (Physics)
    Ben Glick (Molecular Genetics and Cell Biology)
  • May 8: Disequilibrium: Forces and movement
    Wendy Zhang (Physics)
    Ron Rock (Biochemistry and Molecular Biology)
  • May 15: Sequence needles in the genome haystack
    Rick Stevens (Computer Science)
    Yoav Gilad (Human Genetics)
  • May 22: Noise and robustness in signaling networks
    Philippe Cluzel (Physics)
    Marsha Rosner (Ben May Institute for Cancer Research)

Spring Quarter 2003 Cell Physiology 350 Biophysical Discussions: Nucleic Acids
Course Directors: Stephen Kron and Norbert Scherer

  • March 31: Overview of complex behavior and function of nucleic acids
    Steve Kron (Molecular Genetics and Cell Biology)
    Norbert Scherer (Chemistry)
  • April 7: Molecular anatomy of nucleic acids
    Tao Pan (Biochemistry and Molecular Biology)
    Joe Piccirilli (Chemistry)
  • April 14: Base-pair level evolution and repair
    Bernie Strauss (Molecular Genetics and Cell Biology)
    Chuan He (Chemistry)
  • April 21: Nucleic acid sequencing now and in the future
    Edwin Cook (Psychiatry)
    Rustem Ismagilov (Chemistry)
  • April 28: Electrostatic interactions
    Phoebe Rice (Biochemistry and Molecular Biology)
    David Grier (Physics)
  • May 5: Bootstrapping life/evolution
    Jonathan Staley (Molecular Genetics and Cell Biology)
    Philippe Cluzel (Physics)
  • May 12: Hidden information
    San Ming Wang (Hematology and Oncology)
    L. Ridgway Scott (Computer Science; Mathematics)
  • May 19: Forces and recombination in big molecules
    Doug Bishop (Radiation and Cellular Oncology)
    Thomas Witten (Physics)

Spring Quarter 2002 Cell Physiology 350 Biophysical Discussions: Proteins
Course Directors: Dottie Hanck, Stephen Kron, Norbert Scherer, Eric Schwartz

  • March 25: Protein tutorial From synthesis to complexity
    Joe Piccirilli, Chemistry/BMB/HHMI
    Steve Kron, MGCB
  • April 1: Protein discovery + evolution
    Ridg Scott, Comp.Sci./Math/CI/IBD
    Manyuan Long, Ecol.& Evol.
  • April 8: Long time dynamics and photocycles
    Karl Freed, Chemistry/JFI
    Wouter Hoff, BMB
  • April 15: Protein design + chemical synthesis
    Ariel Fernandez, IBD/Chemistry
    Steve Kent, BMB/IBD
  • April 22: Folding
    Steve Berry, Chemistry/JFI
    Tobin Sosnick, BMB/IBD
  • April 29: Protein–ligand interactions
    Sergey Kozmin, Chemistry
    Marsha Rosner, Ben May/Neurobiol. Pharm. & Phys.
  • May 6: William Eaton, NIH Laboratory of Chemical Physics
    Chemistry Harkins Lecture 4:00 pm Kent 120
    “Dynamics and the cure of sickle cell disease”
  • May 7: William Eaton, NIH Laboratory of Chemical Physics
    Burroughs Wellcome Visiting Scholar 3:00 pm – BSLC 240
    "Probing the free energy surface for protein folding with single molecule fluorescence spectroscopy"
  • May 13: Time-resolved structure
    Jim Norris, Chemistry/IBD
    Keith Moffat, BMB/IBD
  • May 20: Protein–protein interactions
    Milan Mrksich, Chemistry/IBD
    Wei-Jen Tang, Ben May
  • May 27: Memorial Day Observed
  • June 3: Proteins and membranes
    Ka Yee Lee, Chemistry/IBD/JFI
    William Green, Neurobiol. Pharm. & Phys.

Spring Quarter 2001 Cell Physiology 350 Biophysical Discussions: Membrane Dynamics
Course Instructors: Dottie Hanck, Stephen Kron, Norbert Scherer, Eric Schwartz

  • March 26:
    Ka Yee Lee (Chemistry)
    Theodore Steck (BMB)
  • April 2:
    David Grier (Physics)
    Eric Schwartz (Neuro. Pharm. Phys.)
  • April 9:
    Sidney Nagel (Physics)
    Steve Kron (MGCB)
  • April 16:
    Milan Mrkisch (Chemistry)
    Elizabeth McNally (Medicine)
  • April 23:
    Tom Witten (Physics)
    Eric Beyer (Medicine)
  • April 30:
    Frank Brown (IBD Fellow)
    Aaron Turkewitz (MGCB)
  • May 7:
    Philippe Cluzel (Physics)
    Benjamin Glick (MGCB)
  • May 14:
    David Oxtoby (Chemistry)
    Clive Palfrey (Neuro. Pharm. Phys.)
  • May 21:
    Manfred Lindau (Cornell Univ.)
  • June 4:
    Erwin Neher (MPI, Goettingen) Nobel Laureate in Medicine or Physiology, 1991

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